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KMID : 0376219860230030445
Chonnam Medical Journal
1986 Volume.23 No. 3 p.445 ~ p.452
The Prenatal Development of the Skeleton and Joints of the Human Hand



Abstract
Histological and radiographic observations were done in evaluating the fetal developmental process of the skeleton and joints of the human hand with twenty Korean fetuses of 20mm to 300mm length (crown-rump measurement).
Chondrification of the distal extremities of the radius and ulna, carpals, metacarpals, and phalanges was completed at 30mm.
A primary bone collar of metacarpals and phalanges was first seen at 35mm. The endochondral ossification of metacarpals and phalanges was first noted at 40mm. As endochondral ossification proceeded proximally and distally, and periosteal bone formation also proceeded longitudinally, until about 220mm, and extended about 1~2mm= beyond the zone of bony trabeculae of endochondral ossification. After 260mm, the extents of endochondral and subperiosteal ossification were the same and at term occupied three-fourth of " the length of the metacarpal bones and phalanges.
Cartilage canals of the carpal bones were first seen in scaphoid and capitate at 70xn and in all carpal at 160mm.
Primitive joint cavities of radiocarpal and midcarpal joints were present around the periphery of the joint at 40mm and were completed at 100mm. Synovial tissue was observed to have the vascular invasion at 30mm, formation of the synovial fold and sheath at 60mm.
Cartilaginous sesamoids of the thumb were first found at 40mm. Accessory centrally and triangular were noted at 40mm and 60mm, respectively.
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